Engineering controls serve as the backbone of the compounding operation. Just as every compounding operation is unique, there is no standard approach to the utilization of engineering controls. While LAFWs are widely used and Type II A2 BSCs are quite common, an array of additional equipment options serve to support effective cleanroom operations.

Note that the terms Compounding Aseptic Isolators (CAIs) and Compounding Aseptic Containment Isolators (CACIs) have been replaced with the term Restricted Access Barrier Systems (RABS) as it is a more apt description of this technology and also avoids any confusion with the similarly named, but very different pharmaceutical isolators. These isolators are typically used in pharmaceutical manufacturing and feature a built-in, automated decontamination system. A few hospital pharmacies have adopted this advanced technology in their cleanrooms and we will watch to see if this trend continues.