Spill preparedness is critical to successfully avoiding hazardous drug exposure. Hope for the best but prepare for the worst with prepackaged Chemo Spill Kits, designed to handle spills of cytotoxic drugs in accordance with the guidelines provided by ASHP. Kits include recommended PPE along with ChemoPlus absorbent pads, signage, and waste bags. According to ASHP, a spill kit should accompany delivery of injectable hazardous drugs to patient care areas even when they are transported in a sealable container. Signs should also be available to warn of restricted access to the spill area.